Senior Software Engineer - Machine Learning (f/m/d)

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.  Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.    ABOUT ISO Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.   Your Impact We are building the largest foundation models in biotech and applying them immediately to cure disease. You will play a pivotal role in ensuring the reliability and scalability of the foundations that make this possible. As a Principal Engineer, you will lead the efforts to harden our systems, ensuring our groundbreaking AI is built on an unshakeable base, working closely with the research team and the Applied ML teams to ensure the infrastructure is stable, reliable and can operate with more data and larger models as we grow.  What You Will Do * Develop and operate our inference platform, serving fleets of cutting-edge machine learning models to scientific applications. * Design strategy and build roadmaps for maturing the platform. * Architect and optimize our next-generation inference services. You will solve core scaling limits, ensuring high-throughput performance and feature parity across our model serving stack. * Contribute to core technical decisions on tooling and architectural design while partnering with science, product, and operations teams to align infrastructure with biotech R&D cycles. * Deliver high-quality and well-tested user-focused features. Skills and Qualifications Essential: * Proven experience in architecting and managing large-scale AI/ML workloads in a production environment. * Expertise in cloud compute design, specifically within Google Cloud Platform (GCP). * Orchestration: Significant experience deploying and managing complex workloads within Kubernetes (GKE). * Professional familiarity with NVIDIA GPU generations and the intricacies of high-performance compute. * Strong programming skills and a "reliability-first" approach to software development. Nice to Have: * A career history that spans both ML Software Engineering and Infrastructure SRE roles. * Experience leading multi-disciplinary projects and navigating complex stakeholder requirements in a fast-paced environment. * Familiarity with workload scheduling, ML efficiency research, and hardware benchmarking. * Experience with Google TPU generations and specialized ML-driven R&D cycles. CULTURE AND VALUES We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.  Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. CREATING AN EXTRAORDINARY COMPANY We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. HYBRID WORKING It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our privacy policy. >> Click to view other open roles at Isomorphic Labs

SUPER PAYMENTS Our mission is to use data and AI to make payments free for businesses, so that everyone wins. By removing payment fees and passing savings back to customers, we are disrupting the payments industry while helping businesses increase sales and loyalty. With Buy Now, Pay Later (BNPL) free for merchants and 0% card payment processing, Super gives businesses a powerful way to reduce costs, grow sales, and reward customers. Already trusted by thousands of businesses and more than 4 million customers, Super is growing fast, supported by leading investors including Accel, Union Square Ventures and LocalGlobe, and led by Samir Desai, founder and former CEO of Funding Circle. OUR VALUES * Customer obsessed: We only succeed when our customers do. * Move fast: Build, test and improve quickly. Progress matters more than perfection. * Own it: Be accountable, solve problems, and make it happen. * Be open: Act with honesty and respect. Transparency builds trust. * Win together: Collaboration beats ego every time.   Our Technology We leverage the latest tools and technologies to create a seamless, customer-centric digital experience. Our core stack is built around Node.js, TypeScript, and NestJS, with a front-end powered by React. We deploy using AWS cloud services and Kubernetes, ensuring scalability and resilience. Infrastructure as Code is fundamental to our approach, and we use Terraform to manage our cloud resources. Our architecture is cloud-native, event-driven, and distributed, built on Amazon EventBridge and SQS, with services exposed via REST. We are driven by data science, machine learning, and analytics, using multi-variant testing to personalise user experiences across every digital channel. However, it’s not just about the technology. We are passionate about continuous delivery, automation, and rapid iteration. Our deployment pipeline is fully automated, covering everything from branching, building, testing, and shipping to monitoring and alerting—allowing us to focus on delivering value to our customers. Technology is at the heart of our business, and we value diverse perspectives. Bring your ideas, experience, and problem-solving mindset—we’ll navigate obstacles together. WHAT YOU’LL BE DOING * Spearheading the design and evolution of our B2B API, personalisation and payments infrastructure. * Collaborating with UX and product teams in discovery, ideation, and problem-solving. * Contributing to engineering-wide initiatives, participating in technical discussions, architecture decisions, and best practice sharing. * Developing a deep understanding of our business, customers, and domain—applying your judgement to make autonomous decisions. * Mentoring and supporting the growth of our engineering community, sharing knowledge through pairing, talks, and external speaking opportunities. We’d love to hear from you if you: * Have at least 8 years of experience in software engineering. * Have worked on any one of the following areas: * Financial Services in areas like payments/wealth management/banking * The payments infrastructure at a large eCommerce site * High-volume transaction scale-up (e.g., betting, gaming, or streaming) * Have a delivery-focused mindset, using agile practices to drive team success. * Bring experience with a variety of programming languages. * Are willing to work with Node.js, TypeScript, NestJS, and AWS cloud technologies. * Have experience designing and provisioning cloud-based infrastructure, using Infrastructure as Code (Terraform). Ideally, have worked with Kubernetes and understand the fundamentals of containerized deployments. * Have built and supported publicly accessible REST APIs. * Understand application development, continuous delivery, test automation, and security within distributed services. * Have a track record of improving code quality, performance, stability, and scalability. * Are comfortable working in a fast-paced, evolving start-up environment. * Can work independently, tackling ambiguous challenges and driving solutions forward. To learn more about about engineering at Super Payments follow this link. https://gist.github.com/sam-super/9c40d3d23fa577ed2e96f2ca68f1d639 *The stated experience and background is a guide and does not preclude applications from candidates with more or less experience, provided the requisite skills can be demonstrated. Our Benefits - here’s a few and more to come …. * Tax advantage Share Options * Flexible working model * Work from home set up * Learning & Development opportunities * Contributory Pension Scheme * Free Team lunch (Tues & Thurs) and social evenings * Comprehensive PMI & x4 Life Insurance * Your birthday off, plus one Revival day If you are excited about sharing the adventure, joining a growing team with big ambitions and you are really great at what you do, then apply now! Super Payments is an equal opportunity employer, embracing diversity in all its forms and fostering an inclusive environment. The company will not unlawfully discriminate on grounds of gender, sexual orientation, marital or civil partner status, gender reassignment, race, religion or belief, colour, nationality, ethnic or national origin, disability or age, neurodiversity status, pregnancy or trade union membership.  Please let us know if you require any reasonable adjustments at any point during the application and/or recruitment process.