Senior Scientist Bioscience - konsultuppdrag Astrazeneca

Are you a curious scientist with experience in mass spectrometry and knowledge of a wide range of biochemical assay methods? Do

you enjoy working hands-on in the lab in collaboration with a great team to push the boundaries of science? If yes, this is the

position for you!

An exciting opportunity has arisen for a highly motivated Senior Scientist to join the Biochemical Assay Development team in the

Assay, Profiling & Cell Sciences department within BioPharmaceuticals R&D, Discovery Sciences in Gothenburg, Sweden. This is a

temporary position for 12 months with preferable starting date before 1st of July.

The Biochemical Assay Development team is responsible for the generation of novel biochemical and cellular assays to support

projects in the early phases of the drug discovery pipeline. This is an opportunity for you to join the group as a lab-based

scientist and be a key member of the team, developing biochemical assays for compound screening and mechanism-of-action studies in

support of small molecule drug discovery projects.

We are looking for a candidate with experience around development of assays with the application of mass spectrometry in

particular small molecules and peptides. Leading from the bench, you will apply your expertise and a passion for driving

scientific questions, combined with strong team working ethics, to drug discovery projects.

What you will do:

In this role you will work as a lab-based scientist, delivering expertise in the area of biochemical

assay development; independently designing, developing and validating biochemical assays for

implementation in drug discovery projects, while incorporating the views of others. You will also

further develop our internal mass spectrometry capability with implementation on existing and

development of novel applications for screening and mechanism of action profiling.

We also want you to be an effective member of Drug Discovery Project Teams, contributing novel

ideas and using judgment and knowledge where appropriate to influence the work of the project.

Other responsibilities:

• To implement work-plans over agreed timelines such that the objectives of the project are met, including delivery of more than

one agreed area of work in parallel where appropriate.

• To maintain an awareness of current developments in the literature and contribute to the continuous improvement process by

identifying opportunities in the workplace where improvements can be made; may lead one or more aspects of scientific discipline

within the team.

Essential in the role:

• Ph.D. in Biology, Pharmacology, Biochemistry or a related discipline or a MSc degree with significant relevant experience.
• Expertise in mass spectrometry, working with detection of enzymatic reactions.
• A practical understanding of a wide range of biochemical assay methods and technologies (not limited to mass spectrometry, for

example fluorescence and luminescence techniques) as applied to a range of biological targets.

• Excellent problem-solving skills, good scientific judgement and communication skills.
• Excellent team working and networking skills with experience of interacting effectively across interfaces of discipline,

culture, and expertise.

Desirable in the role:

• A practical understanding of assay optimisation, including statistical tools such as factorial experimental design, to enable

generation of robust, reproducible and sensitive assays.

• Experience of working in external collaborations.

Why AstraZeneca

At AstraZeneca, we follow the science to explore and innovate. We are committed to treating, preventing, modifying and even curing

some of the world's most complex diseases. Our team is driven by our desire to understand and reveal new insights. We are always

learning from those living with diseases and harnessing digital, data science & AI to fast-forward our research. Join us as we

push the boundaries of science to deliver life-changing medicines.